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For Laboratory Research Use Only — Not For Human Consumption — Not A Drug, Food, Or CosmeticFor Laboratory Research Use Only — Not For Human Consumption — Not A Drug, Food, Or CosmeticFor Laboratory Research Use Only — Not For Human Consumption — Not A Drug, Food, Or CosmeticFor Laboratory Research Use Only — Not For Human Consumption — Not A Drug, Food, Or CosmeticFor Laboratory Research Use Only — Not For Human Consumption — Not A Drug, Food, Or CosmeticFor Laboratory Research Use Only — Not For Human Consumption — Not A Drug, Food, Or CosmeticFor Laboratory Research Use Only — Not For Human Consumption — Not A Drug, Food, Or CosmeticFor Laboratory Research Use Only — Not For Human Consumption — Not A Drug, Food, Or CosmeticFor Laboratory Research Use Only — Not For Human Consumption — Not A Drug, Food, Or CosmeticFor Laboratory Research Use Only — Not For Human Consumption — Not A Drug, Food, Or CosmeticFor Laboratory Research Use Only — Not For Human Consumption — Not A Drug, Food, Or CosmeticFor Laboratory Research Use Only — Not For Human Consumption — Not A Drug, Food, Or Cosmetic
LC RESEARCH CO.
Premium Research Peptides
RT-GLP-3 research vial
LC RESEARCH
RT-GLP-3
30MG
99% PURITY
FOR RESEARCH PURPOSES ONLY
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RT-GLP-3

LC-RETA-30 · 30mg vial

Triple agonist (GLP-3) of the glucagon, GIP, and GLP-1 receptors under investigation for metabolic and adiposity research.

Purity

99%

Availability

In Stock

$100.00

1

Molecular Formula
C221H342N46O68
Molecular Weight
4731.33 g/mol
Sequence
YXQGTFTSDYSILLDKKAQXAFIEYLLEGGPSSGAPPPS
Half-Life
~120 hrs
Physical Form
Lyophilized powder
Storage
-20°C, protect from light
Purity (HPLC)
99%
SKU
LC-RETA-30

Research Dossier

RT-GLP-3 — Preclinical Profile

A plain-language mechanism of action and a general laboratory research protocol — compiled from published research literature.

LC-RETA-30

For laboratory research only. The information below summarizes published research literature and is provided for reference by qualified laboratory personnel. It is not medical advice and makes no therapeutic claims. These products are not for human or veterinary use, diagnosis, or treatment, and have not been evaluated by the FDA.

Mechanism of Action

This compound works by attaching to three different signaling points on the surface of cells. By activating these three specific receptors at the same time, it helps the cell coordinate how it processes energy and sugar. This triple-action approach allows researchers to study how multiple metabolic signals interact within a single molecular framework.

Primary Research Areas

Triple-receptor signaling pathwaysMolecular stability and peptide acylationEnergy expenditure and metabolic regulationHepatic lipid metabolismIncretin-based receptor cross-talk

Clinical Research Applications

Obesity Management

Clinical research is investigating the impact of triple-receptor agonism on body weight reduction over extended periods in human subjects.

Glycemic Regulation

Researchers are evaluating how the compound influences blood sugar markers and insulin sensitivity in individuals with metabolic dysfunction.

Hepatic Steatosis

Ongoing studies are exploring the peptide's effect on liver fat content and metabolic-associated steatotic liver disease markers.

Body Composition

Clinical trials are examining changes in fat mass versus lean mass during multi-receptor activation to understand energy partitioning.

Cardiovascular Outcomes

Research is being conducted to observe the long-term effects of this peptide class on heart health and related cardiometabolic markers.

The applications above describe areas of ongoing clinical investigation reported in the research literature. They are not indications of approved use, efficacy, or safety, and do not constitute medical or therapeutic claims.

Laboratory Research Protocol

Reconstitution

Reconstitute the lyophilized vial using sterile bacteriostatic water or 0.9% sodium chloride solution, directing the liquid down the side of the vial to avoid agitation.

Storage

Store the lyophilized powder at -20°C for long-term stability; once reconstituted, store at 2-8°C and protect from light.

In-vitro reference range

Research literature reports an EC50 of approximately 0.04 nM at the GLP-1 receptor in cAMP-based cell assays (Coskun et al., J Med Chem 2022).

Handling notes

Avoid repeated freeze-thaw cycles and protect from moisture; handle only in controlled laboratory environments by qualified personnel.

Concentration ranges reflect values reported in published in-vitro assays and are provided as a literature reference only — not a dosing regimen for use in any organism.

Selected References

  • 01Retatrutide (Reta GLP-3) - 99%+ Purity — https://northlinelabs.org/product/reta-glp-3
  • 02GLP-3 RT — Eon Peptides — https://eonpeptides.com/glp3-dossier?v=2
  • 03GLP-3 RT Research Peptide | 99%+ Purity - GMR Peptides — https://gmrpeptides.com/product/glp-3-rt-research-peptide
  • 04Triple-Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial — https://www.nejm.org/doi/full/10.1056/NEJMoa2301972

Compliance Statement

For laboratory research only, not for human or veterinary use, and not evaluated by the FDA.